Not anymore. Not with 20 game conference seasons, exempt tourneys, conference challenges, gavitt games, and historical local rivalries, etc. They are already committed to playing 90% of their schedule every year before they even start the scheduling process.A P5 will play a good A10 team if they don't have to return the game. You get a nice payday, a big boost if you win, and a loss doesn't do too much damage.
Maybe Wazzu would, but not even VCU or Dayton wants to play Wazzu on any court.